Anomalous Solubility Behavior of Several Acidic Drugs
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چکیده
منابع مشابه
Anomalous Solubility Behavior of Several Acidic Drugs
The “anomalous solubility behavior at higher pH values” of several acidic drugs originally studied by Higuchi et al. in 1953 [1], but hitherto not fully rationalized, has been re-analyzed using a novel solubilitypH analysis computer program, pDISOL-X TM . The program internally derives implicit solubility equations, given a set of proposed equilibria and constants (iteratively refined by weight...
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ژورنال
عنوان ژورنال: ADMET & DMPK
سال: 2014
ISSN: 1848-7718
DOI: 10.5599/admet.2.1.30